Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20038548 | 0.79 | — | — | |
| SCHEMBL24704342 | 0.75 | CHRM5 (0.44) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL20037759 | 0.75 | — | — | |
| SCHEMBL20037947 | 0.72 | LTA4H (0.34) | — | |
| SCHEMBL26358219 | 0.72 | CHRM5 (0.41) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL20038616 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL20037749 | 0.71 | CA12 (0.31) | — | |
| SCHEMBL1126801 | 0.70 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL7228712 | 0.70 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1 | |
| SCHEMBL20038462 | 0.70 | CA2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |