Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731822 | 0.81 | MEN1 (0.60) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3634800 | 0.81 | MLYCD (0.40) | KMT2AMLYCDOXTRMAPTHDAC1 | |
| SCHEMBL16454352 | 0.79 | HDAC1 (0.39) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17333657 | 0.73 | MEN1 (0.76) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20037880 | 0.72 | TP53 (0.38) | KMT2ASMN1; SMN2MLYCDMAPTHDAC1 | |
| SCHEMBL10566572 | 0.71 | MEN1 (0.49) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8915053 | 0.71 | MEN1 (0.46) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13942706 | 0.70 | ALDH1A1 (0.45) | KMT2AMEN1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL2241922 | 0.69 | HDAC1 (0.42) | KMT2ASMN1; SMN2POLBMAPTHDAC1 | |
| SCHEMBL20038435 | 0.69 | MLYCD (0.37) | CYP3A4CYP2C9CYP2C19MLYCDOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |