Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037578 | 0.81 | MPO (0.39) | CHRNB2CHRNA4 | |
| SCHEMBL2135639 | 0.81 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL18291575 | 0.80 | HRH3 (0.33) | — | |
| SCHEMBL20038049 | 0.79 | CHRNB2 (0.31) | CHRNB2CHRNA4 | |
| SCHEMBL20249233 | 0.79 | CYP4F2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL6138308 | 0.77 | CHRNB1 (0.40) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| SCHEMBL6138305 | 0.76 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL6138601 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL18291222 | 0.75 | MPO (0.37) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL30114459 | 0.75 | CHRNB2 (0.41) | CHRNB2CHRNA4CHRNB1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |