Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.64 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.58 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289187 | 0.94 | RAB9A (0.58) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL1491229 | 0.91 | OPRD1 (0.65) | OPRD1OPRK1DRD3CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL27914610 | 0.89 | OPRD1 (0.64) | OPRD1OPRK1DRD3CHRM2ADRA2A | |
| SCHEMBL9613663 | 0.87 | HRH1 (0.78) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL1405261 | 0.85 | DRD3 (0.76) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL13845055 | 0.85 | DRD3 (0.76) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL10367443 | 0.85 | DRD3 (0.60) | OPRD1OPRK1DRD3CHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL5113093 | 0.84 | DRD3 (0.74) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| Hydrochloric Acid SCHEMBL6475984 | 0.83 | DRD3 (0.73) | OPRD1CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL6618656 | 0.81 | DRD3 (0.63) | OPRD1OPRK1DRD3CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013323-B1 | COMPLEX GRANULE FORMULATION HAVING IMPROVED STABILITY COMPRISING LEVOCETIRIZINE AND MONTELUKAST | HANMI PHARM IND CO LTD (KR) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019004776-A2 | COMPOSITE CHEWABLE TABLET INCLUDING LEVOCETIRIZINE AND MONTELUKAST WITH IMPROVED STABILITY AND DRUG COMPLIANCE, AND METHOD OF PREPARING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2019-01-03 | — | — | WO | disclosed |
| EP-2800558-B1 | STABLE PHARMACEUTICAL FORMULATION FOR ORAL ADMINISTRATION COMPRISING LEVOCETIRIZINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND MONTELUKAST OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | HANMI PHARM IND CO LTD (KR) | 2018-04-11 | — | — | EP | disclosed |