Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102129 | 0.76 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL27909545 | 0.76 | SOS1 (0.51) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| Hydrochloric Acid SCHEMBL28065788 | 0.75 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL13541817 | 0.73 | KCNH2 (0.49) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL6247785 | 0.73 | GNAI3 (0.73) | GNAI3GNAO1GNAI1SOS1ALDH1A1 | |
| SCHEMBL8682833 | 0.73 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SOS1KCNH2 | |
| SCHEMBL20648825 | 0.73 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SOS1ALDH1A1 | |
| SCHEMBL20932984 | 0.72 | GNAI3 (0.49) | GNAI3GNAO1GNAI1SOS1KDM4E | |
| SCHEMBL19560897 | 0.71 | GNAI3 (0.61) | GNAI3GNAO1GNAI1SOS1ALDH1A1 | |
| SCHEMBL8851009 | 0.71 | GNAI3 (0.56) | GNAI3GNAO1GNAI1SOS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091012-B1 | CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF | CENTREXION THERAPEUTICS CORP (US) | 2018-04-11 | — | — | EP | disclosed |