Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040343 | 0.92 | KMT2A (0.39) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL20040445 | 0.86 | KMT2A (0.52) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL20040349 | 0.84 | KMT2A (0.35) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL15006373 | 0.84 | KMT2A (0.40) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL20040323 | 0.79 | KMT2A (0.36) | KMT2AMAPTMEN1MGLL | |
| SCHEMBL11926959 | 0.78 | FOLH1 (0.44) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL20040345 | 0.77 | KMT2A (0.38) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL15259411 | 0.72 | ALB (0.42) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL20040344 | 0.72 | MGLL (0.39) | KMT2ANPC1RAB9AMEN1MGLL | |
| SCHEMBL20040348 | 0.70 | KMT2A (0.34) | KMT2AKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |