Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040346 | 0.82 | SIRT1 (0.34) | MGLLMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11921777 | 0.74 | CTSL (0.39) | RAB9ACTSL | |
| SCHEMBL20040297 | 0.72 | KMT2A (0.41) | MGLLMEN1KMT2ANPC1RAB9A | |
| SCHEMBL16270215 | 0.71 | KMT2A (0.43) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL16270250 | 0.71 | KMT2A (0.43) | MEN1KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL11921759 | 0.68 | TSHR (0.42) | ADRB2ADRB1ADRB3NPC1RAB9A | |
| SCHEMBL20040343 | 0.67 | KMT2A (0.39) | MGLLMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20040351 | 0.67 | NPC1 (0.48) | KMT2ANPC1RAB9AFOLH1 | |
| SCHEMBL11925982 | 0.66 | TSHR (0.41) | RAB9AMMP2MMP3CTSL | |
| SCHEMBL20040349 | 0.66 | KMT2A (0.35) | MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |