Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637837 | 0.78 | NOTUM (0.43) | MAPTNOTUM | |
| SCHEMBL20040880 | 0.71 | KDR (0.46) | NOTUM | |
| SCHEMBL28642986 | 0.63 | SLC18A3 (0.36) | — | |
| SCHEMBL330354 | 0.63 | MAPT (0.55) | IDO1MAPT | |
| SCHEMBL20040714 | 0.62 | KIF11 (0.44) | IDO1MAPT | |
| SCHEMBL15611355 | 0.62 | HTR2C (0.44) | NOTUM | |
| Hydrochloric Acid SCHEMBL1968509 | 0.61 | MAPT (0.53) | IDO1MAPT | |
| SCHEMBL15562144 | 0.61 | NOTUM (0.53) | IDO1NOTUM | |
| SCHEMBL6898414 | 0.61 | KDR (0.47) | NOTUM | |
| SCHEMBL15787494 | 0.61 | NOTUM (0.39) | IDO1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |