Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908579 | 0.89 | HTR2C (0.35) | SLC18A3 | |
| SCHEMBL22942460 | 0.84 | MEN1 (0.32) | TSHR | |
| SCHEMBL28637837 | 0.82 | NOTUM (0.43) | — | |
| SCHEMBL22083034 | 0.82 | EGLN2 (0.35) | TSHR | |
| SCHEMBL26898819 | 0.80 | PRKCI (0.43) | TSHR | |
| SCHEMBL28926824 | 0.80 | CNR2 (0.34) | — | |
| SCHEMBL28637820 | 0.80 | TSHR (0.32) | TSHRPOLB | |
| SCHEMBL28645681 | 0.78 | DHODH (0.34) | — | |
| SCHEMBL27796045 | 0.78 | KDM4E (0.43) | SLC18A3 | |
| SCHEMBL13844335 | 0.77 | SLC18A3 (0.54) | SLC18A3ESR2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412113-A | Aminooxazine amides | 豪夫迈·罗氏有限公司 | 2021-09-17 | — | — | CN | disclosed |