Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040880 | 0.88 | KDR (0.46) | NOTUMHTR2CDRD2IDH2BRAF | |
| SCHEMBL28642986 | 0.82 | SLC18A3 (0.36) | — | |
| SCHEMBL15562144 | 0.80 | NOTUM (0.53) | NOTUMHTR2CPTPN5DRD2CNR1 | |
| SCHEMBL16729426 | 0.79 | NOTUM (0.46) | NOTUMHTR2CPTPN5DRD2RAPGEF4 | |
| SCHEMBL330354 | 0.78 | MAPT (0.55) | KIF11MAPTRAPGEF4IDH2 | |
| SCHEMBL20040975 | 0.78 | CXCR3 (0.33) | NOTUMMAPT | |
| Hydrochloric Acid SCHEMBL1968509 | 0.76 | MAPT (0.53) | KIF11MAPTRAPGEF4IDH2 | |
| SCHEMBL6898414 | 0.76 | KDR (0.47) | NOTUMHTR2CDRD2IDH2BRAF | |
| SCHEMBL13197438 | 0.76 | ESR2 (0.47) | NOTUMHTR2CPTPN5DRD2CNR1 | |
| SCHEMBL13197440 | 0.76 | ESR2 (0.47) | NOTUMHTR2CPTPN5DRD2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113412113-A | Aminooxazine amides | 豪夫迈·罗氏有限公司 | 2021-09-17 | — | — | CN | disclosed |