SCHEMBL200411

SCHEMBL200411

CC(C)Sc1cccc(SC(C)C)c1[O]

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAP2K7 O14733 2/20 0.42
CDC25A P30304 2/20 0.42
CDC25B P30305 2/20 0.42
ADRA2A P08913 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
ELANE P08246 1/20 0.32
CETP P11597 1/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274942 0.81 CA2 (0.39) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL30548758 0.80 MAP2K7 (0.41) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL200412 0.77 GABRA1 (0.43) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL1275574 0.75 AR (0.31)
SCHEMBL4654999 0.72 MAP2K7 (0.36) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL30291966 0.72 ACHE (0.43) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL10297569 0.72 ACHE (0.43) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL21852053 0.72 CYP1A2 (0.45) ALDH1A1
SCHEMBL21423238 0.72 ACHE (0.38) MAP2K7CDC25ACDC25BADRA2AADRA2B
SCHEMBL2116696 0.72 IFNAR1 (0.43) ELANEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3363824-B1 MULTICOMPONENT COPOLYMER, RUBBER COMPOSITION, CROSS-LINKED RUBBER COMPOSITION, RUBBER PRODUCT, AND TIRE BRIDGESTONE CORP (JP) 2024-05-01 EP disclosed
EP-3954549-B1 POLYISOPRENE, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2023-12-13 EP disclosed
CN-113677543-B Polyisoprene, rubber composition and tire 株式会社普利司通 2023-04-28 CN disclosed
EP-3363831-B1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, RUBBER PRODUCT AND TIRE BRIDGESTONE CORP (JP) 2023-02-01 EP disclosed
EP-3363832-B1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, RUBBER PRODUCT, AND TIRE BRIDGESTONE CORP (JP) 2023-01-25 EP disclosed
US-11518831-B2 Method for producing multicomponent copolymer, multicomponent copolymer, rubber composition, and tire BRIDGESTONE CORPORATION (JP) 2022-12-06 US disclosed
US-20220220238-A1 METHOD FOR MANUFACTURING COPOLYMER BRIDGESTONE CORPORATION (JP) 2022-07-14 US disclosed
US-20220213240-A1 MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE, AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2022-07-07 US disclosed
CN-110536907-B Method for producing multipolymer, rubber composition and tire 株式会社普利司通 2022-06-17 CN disclosed
US-20220185921-A1 POLYISOPRENE, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORPORATION (JP) 2022-06-16 US disclosed
EP-1541593-A1 CATALYST COMPOSITION RIKEN (JP) 2005-06-15 EP disclosed
EP-1512700-A1 POLYMERIZATION CATALYST RIKEN (JP) 2005-03-09 EP disclosed
EP-1500667-A1 CATALYST COMPOSITION Riken (JP) 2005-01-26 EP disclosed
US-6683140-B2 Catalyst for polymerization RIKEN (JP) 2004-01-27 US disclosed
US-20030166458-A1 Block copolymerization of a conjugated diene and an aromatic vinyl compound, which comprises the steps of carrying out homopolymerization of the conjugated diene in the presence of a catalyst composition comprising the following RIKEN (JP) 2003-09-04 US disclosed
US-6596828-B1 polymerization of a conjugated diene or copolymerization of a conjugated diene and an aromatic vinyl compound, which comprises the following components: (A) a metallocene-type complex of a rare earth metal compound (samarium complex RIKEN (JP) 2003-07-22 US disclosed
US-20030018144-A1 Catalyst composition RIKEN (JP) 2003-01-23 US disclosed
EP-1270626-A1 CATALYST COMPOSITION AND PROCESS FOR PRODUCING COPOLYMER Riken (JP) 2003-01-02 EP disclosed
US-20020119889-A1 Catalyst for polymerization RIKEN (JP) 2002-08-29 US disclosed
EP-1086957-A1 CATALYST COMPOSITION Riken (JP) 2001-03-28 EP disclosed