Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041101 | 0.86 | AKT1 (0.45) | ALDH1A1POLBOPRD1OPRM1OPRK1 | |
| SCHEMBL17178203 | 0.84 | CHRNA1 (0.44) | — | |
| SCHEMBL25730738 | 0.84 | LMNA (0.40) | ALDH1A1CPA1CPA2CPA4 | |
| SCHEMBL21152554 | 0.83 | ACE (0.40) | OPRD1OPRM1OPRK1ACE | |
| SCHEMBL16485173 | 0.81 | CHRNB2 (0.48) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27377107 | 0.80 | CCKAR (0.47) | — | |
| SCHEMBL30360098 | 0.79 | ACE (0.57) | ACE | |
| SCHEMBL16485412 | 0.79 | CHRNA1 (0.42) | — | |
| SCHEMBL27379438 | 0.79 | CCKAR (0.43) | OPRD1OPRM1OPRK1 | |
| SCHEMBL27379451 | 0.79 | CCKAR (0.43) | OPRD1OPRM1OPRK1CPA1CPA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020164-A2 | GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF | FIREFLY BIO, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2020132483-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2019217591-A1 | ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-11-14 | — | — | WO | disclosed |
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |