Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041622 | 0.92 | NPC1 (0.41) | NPC1RAB9AALOX5FLT3FAAH | |
| SCHEMBL17507362 | 0.89 | ALOX5 (0.50) | NPC1RAB9AALOX5FLT3PRKDC | |
| SCHEMBL20041625 | 0.87 | NPC1 (0.41) | NPC1RAB9AALOX5FLT3PRKDC | |
| SCHEMBL17507387 | 0.81 | ALOX5 (0.49) | NPC1RAB9AALOX5FLT3PRKDC | |
| SCHEMBL20041416 | 0.79 | FLT3 (0.41) | NPC1RAB9AALOX5FLT3PRKDC | |
| SCHEMBL20041609 | 0.77 | NPC1 (0.45) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507364 | 0.76 | NPC1 (0.44) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL20041610 | 0.75 | NPC1 (0.51) | NPC1RAB9ABACE1ALDH1A1KDM4E | |
| SCHEMBL20041465 | 0.75 | NPC1 (0.43) | NPC1RAB9APDE10A | |
| SCHEMBL17507363 | 0.75 | NPC1 (0.54) | NPC1RAB9ABACE1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |