Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041464 | 0.84 | TSHR (0.70) | TSHRLMNAGAAALDH1A1MAPK1 | |
| SCHEMBL20041714 | 0.82 | TSHR (0.58) | TSHRLMNANPC1RAB9AGAA | |
| SCHEMBL1104809 | 0.78 | HTT (0.69) | TSHRNPC1ALDH1A1MAPK1HTT | |
| SCHEMBL1708108 | 0.72 | POLB (0.53) | TSHRLMNARAB9AGAAALDH1A1 | |
| SCHEMBL15631604 | 0.72 | TSHR (0.71) | TSHRLMNANPC1RAB9AGAA | |
| SCHEMBL19486460 | 0.71 | TSHR (0.82) | TSHRLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL6135958 | 0.70 | NPC1 (0.71) | LMNANPC1RAB9AGAAALDH1A1 | |
| SCHEMBL13080878 | 0.70 | TSHR (0.73) | TSHRLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL31259081 | 0.69 | HCAR1 (0.51) | TSHRLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL26528200 | 0.69 | NQO2 (0.39) | TSHRLMNARAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |