Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513221 | 1.00 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL18513281 | 1.00 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL18503740 | 0.90 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL18708184 | 0.90 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL24499107 | 0.82 | LMNA (0.39) | AHCYDOT1LP2RY12ADORA1 | |
| SCHEMBL26626301 | 0.82 | AHCY (0.46) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL20041580 | 0.81 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL18513222 | 0.81 | AHCY (0.45) | AHCYPRMT5WDR77PI4KAPI4K2B | |
| SCHEMBL24499185 | 0.80 | AHCY (0.46) | AHCYDOT1LPRMT5WDR77P2RY12 | |
| SCHEMBL24499158 | 0.79 | AHCY (0.47) | AHCYDOT1LPRMT5WDR77P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3109254-B1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | UNIV OSAKA (JP) | 2018-04-11 | — | — | EP | disclosed |