Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18708184 | 1.00 | AHCY (0.47) | AHCYDOT1LGAAPI4KAPI4K2B | |
| SCHEMBL18513281 | 0.90 | AHCY (0.47) | AHCYDOT1LPI4KAPI4K2BPI4K2A | |
| SCHEMBL20041577 | 0.90 | AHCY (0.47) | AHCYDOT1LPI4KAPI4K2BPI4K2A | |
| SCHEMBL18513221 | 0.90 | AHCY (0.47) | AHCYDOT1LPI4KAPI4K2BPI4K2A | |
| SCHEMBL18708181 | 0.83 | ADORA2A (0.47) | ADORA1P2RY12TSHRADORA3ADORA2B | |
| SCHEMBL18503745 | 0.83 | ADORA2A (0.47) | ADORA1P2RY12TSHRADORA3ADORA2B | |
| SCHEMBL24264132 | 0.79 | PI4K2A (0.51) | AHCYDOT1LGAAPI4KAPI4K2B | |
| SCHEMBL18513222 | 0.78 | AHCY (0.45) | AHCYGAAPI4KAPI4K2BPI4K2A | |
| SCHEMBL13429417 | 0.76 | ADORA3 (0.51) | AHCYDOT1LGAAPI4KAPI4K2B | |
| SCHEMBL23989264 | 0.76 | ADORA3 (0.51) | AHCYDOT1LGAAPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044528-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | OSAKA UNIVERSITY (JP) | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044528-A1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | NSUN2, NCL, NSUN3 | AHCY 2343/4885DOT1L 2686/4885GAA 1144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.