SCHEMBL20041634

SCHEMBL20041634

Cc1cccc2c1oc1nc3ccccc3n12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
KDM4E B2RXH2 5/20 0.41
MAPT P10636 3/20 0.41
POLB P06746 3/20 0.41
LMNA P02545 2/20 0.41
TP53 P04637 2/20 0.41
HSD17B10 Q99714 2/20 0.41
NPC1 O15118 5/20 0.40
RAB9A P51151 5/20 0.40
ALDH1A1 P00352 6/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
HPGD P15428 3/20 0.39
PKM P14618 2/20 0.39
GALR3 O60755 1/20 0.39
NR2F2 P24468 1/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
ADORA1 P30542 1/20 0.37
PDE10A Q9Y233 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22037061 0.82 RAB9A (0.41) TSHRKDM4EMAPTPOLBLMNA
SCHEMBL17507367 0.81 NPC1 (0.40) TSHRKDM4EMAPTPOLBLMNA
SCHEMBL22100073 0.80 KDM4E (0.38) TSHRKDM4EMAPTPOLBLMNA
SCHEMBL17507339 0.79 FLT3 (0.45) TSHRKDM4EMAPTPOLBLMNA
SCHEMBL17507333 0.78 HPGD (0.42) KDM4EMAPTPOLBLMNATP53
SCHEMBL22472385 0.78 ADORA2A (0.40) KDM4EMAPTPOLBLMNATP53
SCHEMBL20041421 0.78 TP53 (0.45) TSHRMAPTLMNATP53HSD17B10
SCHEMBL17507336 0.76 HPGD (0.40) KDM4EMAPTPOLBLMNATP53
SCHEMBL20041533 0.76 TP53 (0.43) TSHRMAPTLMNATP53HSD17B10
SCHEMBL20041619 0.75 TP53 (0.43) TSHRMAPTTP53NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11834459-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-20230389413-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2023-11-30 US disclosed
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-11758807-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2023-09-12 US disclosed
US-20200274081-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-20200274076-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION 2020-06-18 US disclosed
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389413-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 TSHR 192/4885KDM4E 2665/4885MAPT 4879/4885
US-11773320-B2 Organic electroluminescent materials and devices CCNL2, HCN4, HNRNPL TSHR 1154/4885KDM4E 2224/4885MAPT 4585/4885
US-20200274081-A1 Organic Electroluminescent Materials and Devices GLRA3, ESRRG, GLRA1 TSHR 192/4885KDM4E 2665/4885MAPT 4879/4885
US-20200274076-A1 Organic Electroluminescent Materials and Devices CCNL2, HCN4, HNRNPL TSHR 1112/4885KDM4E 2353/4885MAPT 4554/4885
US-20200190103-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES RPS4X, MLX, RPS4Y1 TSHR 150/4885KDM4E 1801/4885MAPT 4880/4885
US-11834459-B2 Host materials for electroluminescent devices RPS4X, MLX, RPS4Y1 TSHR 150/4885KDM4E 1801/4885MAPT 4880/4885
US-11758807-B2 Organic electroluminescent materials and devices GLRA3, ESRRG, GLRA1 TSHR 192/4885KDM4E 2665/4885MAPT 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.