Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 3/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041805 | 0.81 | STAT5B (0.45) | STAT5BFURINPIM1IDO1HDAC1 | |
| SCHEMBL20048213 | 0.69 | STAT5B (0.44) | STAT5BFURIN | |
| SCHEMBL23288540 | 0.66 | SIGMAR1 (0.33) | TSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL20041727 | 0.66 | MAOA (0.50) | STAT5BTSHRHDAC1ALDH1A1HDAC3 | |
| SCHEMBL20048222 | 0.65 | STAT5B (0.46) | STAT5BFURIN | |
| SCHEMBL22096008 | 0.65 | ALDH1A1 (0.67) | STAT5BALDH1A1KDM4EKMT2A | |
| SCHEMBL14397810 | 0.65 | TDP1 (0.46) | STAT5BHDAC1ALDH1A1HDAC3HDAC4 | |
| SCHEMBL14399037 | 0.64 | POLB (0.52) | STAT5BIDO1ALDH1A1KDM4E | |
| SCHEMBL22096016 | 0.62 | STAT5B (0.81) | STAT5BTSHRALDH1A1HDAC6 | |
| SCHEMBL19848691 | 0.61 | IDO1 (0.40) | TSHRIDO1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523297-B1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | UNIV BERLIN FREIE (DE) | 2021-07-07 | — | — | EP | disclosed |
| WO-2018065536-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | FREIE UNIVERSITÄT BERLIN (DE) | 2018-04-12 | — | — | WO | disclosed |
| EP-3305783-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | Freie Universität Berlin (DE) | 2018-04-11 | — | — | EP | disclosed |