Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.38 |
| ▸ | ADH1A | P07327 | 4/20 | 0.38 |
| ▸ | ADH7 | P40394 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392606 | 0.79 | TSHR (0.38) | CA1CA2SMN1; SMN2KMT2ACA14 | |
| SCHEMBL17017527 | 0.79 | GABRR1 (0.52) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL8308294 | 0.78 | ADH1B (0.37) | ADH1BADH1AADH7CA1CA2 | |
| SCHEMBL18827035 | 0.78 | ADH1B (0.37) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL26817767 | 0.78 | THRB (0.37) | SMN1; SMN2 | |
| SCHEMBL7105090 | 0.78 | SMN1; SMN2 (0.46) | CA1CA2SMN1; SMN2KMT2ACA14 | |
| SCHEMBL24770936 | 0.78 | CA1 (0.42) | CA1CA2SMN1; SMN2KMT2ACA14 | |
| SCHEMBL17017531 | 0.78 | ADH1B (0.39) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL23190306 | 0.77 | CA1 (0.41) | CA1CA2SMN1; SMN2KMT2ACA14 | |
| SCHEMBL14306730 | 0.75 | CA1 (0.44) | CA1CA2SMN1; SMN2KMT2ACA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |