Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042294 | 0.81 | MAPT (0.43) | ALDH1A1KMT2AHTTMEN1MAPT | |
| SCHEMBL20042055 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| SCHEMBL5062448 | 0.72 | HTT (0.54) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| SCHEMBL28103119 | 0.72 | HTT (0.57) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| Urethane SCHEMBL2070142 | 0.72 | HTT (0.70) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| SCHEMBL1008451 | 0.72 | HTT (0.60) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| SCHEMBL755761 | 0.71 | FBP1 (0.55) | ALDH1A1KMT2ASMN1; SMN2PPARGPPARA | |
| SCHEMBL5925521 | 0.71 | MAPT (0.62) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 | |
| SCHEMBL4941803 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1KMT2ASMN1; SMN2MEN1TDP1 | |
| Methyl Alcohol SCHEMBL27770206 | 0.71 | HTT (0.68) | ALDH1A1KMT2AHTTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | HDAC1, HDAC5, HDAC9 | ALDH1A1 671/4885KMT2A 31/4885HTT 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.