Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 4/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.31 |
| ▸ | MST1R | Q04912 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | FRK | P42685 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28359602 | 1.00 | ACVR1 (0.31) | ACVR1CLK4MST1RCDK8GSK3A | |
| SCHEMBL23398061 | 0.86 | — | — | |
| SCHEMBL20042379 | 0.85 | ACVR1 (0.32) | ACVR1CLK4MST1RCDK8GSK3A | |
| SCHEMBL21796218 | 0.84 | DDR1 (0.33) | ACVR1CLK4MST1RCDK8GSK3A | |
| SCHEMBL23398053 | 0.82 | ACVR1 (0.30) | ACVR1CLK4MST1RCDK8GSK3A | |
| SCHEMBL21999358 | 0.82 | PIK3CD (0.32) | ACVR1CLK4MST1RCDK8PRKD3 | |
| SCHEMBL18498705 | 0.82 | POLB (0.33) | POLBALDH1A1LMNAMAPT | |
| SCHEMBL23398096 | 0.81 | PRKD3 (0.31) | ACVR1CLK4MST1RCDK8PRKD3 | |
| SCHEMBL21930788 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL18498642 | 0.80 | CYP11B1 (0.35) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110637019-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳公司 | 2022-07-12 | — | — | CN | disclosed |