SCHEMBL20042492

SCHEMBL20042492

NC(N)=C1CC(=O)c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
KDM4E B2RXH2 3/20 0.42
BLM P54132 2/20 0.42
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
PABPC1 P11940 1/20 0.42
HPGD P15428 2/20 0.41
BCHE P06276 1/20 0.39
CES1 P23141 1/20 0.39
MAOA P21397 1/20 0.37
S100A4 P26447 2/20 0.35
FURIN P09958 1/20 0.35
CDC25B P30305 1/20 0.35
APAF1 O14727 1/20 0.34
TDP2 O95551 1/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10046603 0.83 ALDH1A1 (0.55) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL20042500 0.79 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL88188 0.75 CES1 (0.52) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL29353628 0.75 CES1 (0.52) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL806906 0.74 MAPT (0.38) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL29444282 0.74 MAPT (0.38) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL31741221 0.73 CES1 (0.50) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL10556518 0.73 MAOA (0.53) ALDH1A1MEN1KMT2AKDM4EBLM
SCHEMBL14600848 0.72 S100A4 (0.35) ALDH1A1MEN1KMT2AKDM4EBLM
Ammonia Solution, Strong SCHEMBL29011557 0.72 MAPT (0.37) ALDH1A1MEN1KMT2AKDM4EBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481834-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2023-10-18 EP disclosed
WO-2018065356-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed
WO-2018065352-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed
WO-2018065350-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 WO disclosed