Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001323 | 0.95 | L3MBTL1 (0.41) | FAAHALDH1A1LMNAMAPTALOX12 | |
| SCHEMBL2005782 | 0.95 | FAAH (0.43) | FAAHTSHRALDH1A1LMNAMAPT | |
| SCHEMBL2001270 | 0.94 | FAAH (0.41) | FAAH | |
| SCHEMBL2003840 | 0.92 | FAAH (0.40) | FAAH | |
| SCHEMBL1999529 | 0.91 | FAAH (0.40) | FAAHLMNA | |
| SCHEMBL2003243 | 0.90 | FAAH (0.47) | FAAH | |
| SCHEMBL2002866 | 0.89 | FAAH (0.41) | FAAH | |
| SCHEMBL2001356 | 0.89 | FAAH (0.37) | FAAHTSHRALDH1A1LMNAMAPT | |
| SCHEMBL2002487 | 0.88 | LMNA (0.40) | FAAHTSHRALDH1A1LMNAMAPT | |
| SCHEMBL2003934 | 0.86 | KDM4E (0.39) | FAAHTSHRALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |