Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042683 | 0.81 | NPY5R (0.39) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042813 | 0.81 | HTR2C (0.37) | SMN1; SMN2HTR2CPDE4APDE4BPDE4C | |
| SCHEMBL31614818 | 0.81 | NPY5R (0.39) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20042777 | 0.81 | HRH4 (0.38) | HRH1HTR2CHTR2A | |
| Hydrochloric Acid SCHEMBL31405518 | 0.79 | MEN1 (0.39) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL31614730 | 0.79 | MEN1 (0.39) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19358098 | 0.77 | HRH4 (0.41) | — | |
| SCHEMBL20042692 | 0.77 | MTOR (0.37) | USP2HTR2CHTR2ATSHRHSD17B10 | |
| SCHEMBL31615106 | 0.77 | MTOR (0.37) | USP2HTR2CHTR2ATSHRHSD17B10 | |
| SCHEMBL20042648 | 0.77 | CHRM3 (0.51) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |