Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 15/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358098 | 0.97 | HRH4 (0.41) | HRH4CHUKLMNAHRH3NPY5R | |
| Trifluoroacetic Acid SCHEMBL29710241 | 0.83 | LMNA (0.35) | HRH4CHUKLMNAHRH3NPY5R | |
| SCHEMBL20042881 | 0.81 | HRH1 (0.41) | HTR2AHTR2CHRH1 | |
| SCHEMBL20042813 | 0.79 | HTR2C (0.37) | HTR2C | |
| SCHEMBL20042683 | 0.79 | NPY5R (0.39) | NPY5R | |
| SCHEMBL31614818 | 0.79 | NPY5R (0.39) | NPY5R | |
| Hydrochloric Acid SCHEMBL31614730 | 0.78 | MEN1 (0.39) | NPY5R | |
| Hydrochloric Acid SCHEMBL31405518 | 0.78 | MEN1 (0.39) | NPY5R | |
| SCHEMBL20042692 | 0.76 | MTOR (0.37) | HRH4LMNAHTR2AHTR2CHTR2B | |
| SCHEMBL31615106 | 0.76 | MTOR (0.37) | HRH4LMNAHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |