Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414059 | 0.85 | MTOR (0.44) | HTR2CALDH1A1SMN1; SMN2MTOR | |
| Hydrochloric Acid SCHEMBL22718448 | 0.84 | MTOR (0.43) | HTR2CALDH1A1SMN1; SMN2MTOR | |
| SCHEMBL20042881 | 0.81 | HRH1 (0.41) | HTR2CALDH1A1SMN1; SMN2PSDMTOR | |
| SCHEMBL20042683 | 0.79 | NPY5R (0.39) | SMN1; SMN2PSDMTORPDE4APDE4B | |
| SCHEMBL31614818 | 0.79 | NPY5R (0.39) | SMN1; SMN2PSDMTORPDE4APDE4B | |
| SCHEMBL20042777 | 0.79 | HRH4 (0.38) | HTR2C | |
| Hydrochloric Acid SCHEMBL31614730 | 0.78 | MEN1 (0.39) | SMN1; SMN2PSDMTORPDE4APDE4B | |
| Hydrochloric Acid SCHEMBL31405518 | 0.78 | MEN1 (0.39) | SMN1; SMN2PSDMTORPDE4APDE4B | |
| SCHEMBL19358098 | 0.76 | HRH4 (0.41) | — | |
| SCHEMBL20042692 | 0.76 | MTOR (0.37) | HTR2CALDH1A1PSDMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |