Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.51 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042709 | 0.85 | ALDH1A1 (0.53) | PSDMTORUSP2TSHRLMNA | |
| SCHEMBL20042881 | 0.73 | HRH1 (0.41) | PSDMTORUSP2TSHRPDE4B | |
| SCHEMBL20042683 | 0.72 | NPY5R (0.39) | PSDMTORNPY5RMEN1KMT2A | |
| SCHEMBL31614818 | 0.72 | NPY5R (0.39) | PSDMTORNPY5RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31405518 | 0.71 | MEN1 (0.39) | PSDMTORNPY5RMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31614730 | 0.71 | MEN1 (0.39) | PSDMTORNPY5RMEN1KMT2A | |
| SCHEMBL19358098 | 0.69 | HRH4 (0.41) | NPY5RLMNAMAPT | |
| SCHEMBL19358112 | 0.69 | GBA1 (0.43) | PSDMTORNPY5RTSHRMEN1 | |
| SCHEMBL31615106 | 0.69 | MTOR (0.37) | PSDMTORNPY5RUSP2TSHR | |
| SCHEMBL4089260 | 0.68 | ACP1 (1.00) | ACP1USP2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |