Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 8/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042928 | 0.90 | TACR3 (0.44) | KMT2ATACR3KCNH2TACR1CYP1A2 | |
| SCHEMBL20042922 | 0.88 | TACR2 (0.40) | KMT2APOLBTACR3KCNH2CYP2D6 | |
| SCHEMBL20042982 | 0.86 | P2RX7 (0.46) | HSD17B10KMT2APOLBSLC6A7GBA1 | |
| SCHEMBL20042851 | 0.86 | P2RX7 (0.46) | HSD17B10KMT2APOLBSLC6A7GBA1 | |
| SCHEMBL20042864 | 0.84 | HSD17B10 (0.39) | HSD17B10KMT2APOLBSLC6A7TACR3 | |
| SCHEMBL20042989 | 0.82 | SMN1; SMN2 (0.44) | KMT2ATACR3KCNH2CYP1A2CYP2D6 | |
| SCHEMBL20042860 | 0.80 | GRM5 (0.40) | KMT2AALDH1A1MEN1RECQLNPSR1 | |
| SCHEMBL20042740 | 0.78 | HSD17B10 (0.49) | HSD17B10KMT2APOLBSLC6A7GBA1 | |
| SCHEMBL20042910 | 0.78 | P2RX7 (0.42) | HSD17B10KMT2ASLC6A7GBA1TP53 | |
| SCHEMBL20042904 | 0.78 | P2RX7 (0.42) | HSD17B10KMT2ASLC6A7GBA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |