Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042894 | 0.88 | GRM5 (0.40) | GRM5HCRTR1HCRTR2CASRSMO | |
| SCHEMBL20042843 | 0.88 | GRM5 (0.40) | GRM5HCRTR1HCRTR2CASRSMO | |
| SCHEMBL20042922 | 0.86 | TACR2 (0.40) | MEN1ALDH1A1RECQLKMT2ANPSR1 | |
| SCHEMBL20042989 | 0.86 | SMN1; SMN2 (0.44) | GRM5MEN1ALDH1A1KMT2A | |
| SCHEMBL20042932 | 0.86 | GRM5 (0.38) | GRM5HCRTR1HCRTR2CASRSMO | |
| SCHEMBL20042928 | 0.80 | TACR3 (0.44) | GRM5MEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL20042835 | 0.80 | HSD17B10 (0.41) | MEN1ALDH1A1RECQLKMT2ANPSR1 | |
| SCHEMBL20042767 | 0.76 | TACR3 (0.44) | GRM5ALDH1A1 | |
| SCHEMBL20042939 | 0.75 | GRM5 (0.40) | GRM5MEN1ALDH1A1KMT2A | |
| SCHEMBL20042853 | 0.75 | GPR6 (0.34) | HCRTR1HCRTR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |