Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RXRB | P28702 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448814 | 0.85 | SHBG (0.59) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL7825374 | 0.78 | CYP3A4 (0.65) | RXRARXRBNR4A2RARBKMT2A | |
| SCHEMBL19322103 | 0.77 | ALOX15 (0.61) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL19404368 | 0.77 | MAPT (0.46) | SRD5A2RXRARXRBNR4A2RARB | |
| SCHEMBL20224609 | 0.77 | MEN1 (0.49) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL9653084 | 0.76 | SRD5A2 (0.57) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL444583 | 0.76 | MEN1 (0.59) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL13360086 | 0.76 | SRD5A2 (0.57) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL9578933 | 0.76 | SRD5A2 (0.57) | SRD5A2NR1H4RXRARXRBNR4A2 | |
| SCHEMBL2804705 | 0.74 | SRD5A2 (0.55) | SRD5A2NR1H4RXRARXRBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067769-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR INHIBITING BACTERIAL GROWTH | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2018-04-12 | — | — | WO | disclosed |