Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.52 |
| ▸ | KIF11 | P52732 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906153 | 0.84 | SIRT2 (0.63) | SIRT2KIF11 | |
| SCHEMBL14962372 | 0.77 | SIRT2 (0.52) | SIRT2KIF11 | |
| SCHEMBL17933728 | 0.76 | SIRT2 (0.63) | SIRT2KIF11GAA | |
| SCHEMBL11490946 | 0.76 | KIF11 (0.52) | SIRT2KIF11 | |
| SCHEMBL2830189 | 0.74 | SMN1; SMN2 (0.45) | KIF11ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL5666943 | 0.73 | NPC1 (0.48) | SIRT2KIF11ALDH1A1SMN1; SMN2 | |
| SCHEMBL7206096 | 0.73 | KIF11 (0.57) | SIRT2KIF11 | |
| SCHEMBL1648406 | 0.72 | KIF11 (0.50) | KIF11ALDH1A1 | |
| SCHEMBL17345974 | 0.71 | SIRT2 (0.50) | SIRT2KIF11 | |
| SCHEMBL19154882 | 0.71 | SIRT2 (0.50) | SIRT2KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180100036-A1 | CLICK NUCLEIC ACID POLYMERS AND METHODS OF USE | UNIV COLORADO REGENTS (US) | 2018-04-12 | — | — | US | disclosed |