SCHEMBL1906153

SCHEMBL1906153

c1ccc(C(SCCNCCSC(c2ccccc2)(c2ccccc2)c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 3/20 0.63
KIF11 P52732 17/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14962372 0.88 SIRT2 (0.52) SIRT2KIF11
SCHEMBL17933728 0.87 SIRT2 (0.63) SIRT2KIF11
SCHEMBL17345974 0.85 SIRT2 (0.50) SIRT2KIF11
SCHEMBL19154882 0.85 SIRT2 (0.50) SIRT2KIF11
SCHEMBL98808 0.84 KIF11 (0.53) SIRT2KIF11
SCHEMBL20043060 0.84 SIRT2 (0.52) SIRT2KIF11
SCHEMBL7206096 0.83 KIF11 (0.57) SIRT2KIF11
SCHEMBL11490946 0.83 KIF11 (0.52) SIRT2KIF11
SCHEMBL17345933 0.82 SIRT2 (0.48) SIRT2KIF11
SCHEMBL1706149 0.81 SIRT2 (0.47) SIRT2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630494-B1 METHOD FOR FUNCTIONALISING SURFACES FOR ANALYTE DETECTION CENTRE NAT RECH SCIENT (FR) 2020-03-18 EP disclosed
US-9671397-B2 Method for functionalizing surfaces for analyte detection CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-06-06 US disclosed
US-9671397-B2 Method for functionalizing surfaces for analyte detection CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-06-06 US disclosed
US-9029503-B2 Method for native ligation of polypeptides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-05-12 US disclosed
US-9029503-B2 Method for native ligation of polypeptides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-05-12 US disclosed
US-9029503-B2 Method for native ligation of polypeptides CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-05-12 US disclosed
EP-2493909-B1 METHOD FOR NATIVE LIGATION OF POLYPEPTIDES CENTRE NAT RECH SCIENT (FR) 2014-05-21 EP disclosed
EP-2630494-A1 METHOD FOR FUNCTIONALISING SURFACES FOR ANALYTE DETECTION Centre National De La Recherche Scientifique (FR) 2013-08-28 EP disclosed
US-20130203629-A1 METHOD FOR FUNCTIONALIZING SURFACES FOR ANALYTE DETECTION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-08-08 US disclosed
US-20130203629-A1 METHOD FOR FUNCTIONALIZING SURFACES FOR ANALYTE DETECTION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-08-08 US disclosed
EP-2493909-A1 METHOD FOR NATIVE LIGATION OF POLYPEPTIDES Centre National De La Recherche Scientifique CNRS (FR) 2012-09-05 EP disclosed
US-20120220721-A1 Method for Native Ligation of Polypeptides INSTITUT PASTEUR DE LILLE (FR) 2012-08-30 US disclosed
US-20120220721-A1 Method for Native Ligation of Polypeptides INSTITUT PASTEUR DE LILLE (FR) 2012-08-30 US disclosed
US-20120220721-A1 Method for Native Ligation of Polypeptides INSTITUT PASTEUR DE LILLE (FR) 2012-08-30 US disclosed
WO-2012052874-A1 METHOD FOR FUNCTIONALISING SURFACES FOR ANALYTE DETECTION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-04-26 WO disclosed
WO-2012052874-A1 METHOD FOR FUNCTIONALISING SURFACES FOR ANALYTE DETECTION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-04-26 WO disclosed
WO-2011051906-A1 METHOD FOR NATIVE LIGATION OF POLYPEPTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-05-05 WO disclosed
WO-2011051906-A1 METHOD FOR NATIVE LIGATION OF POLYPEPTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2011-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120220721-A1 Method for Native Ligation of Polypeptides HAX1, PTMS, MLX SIRT2 2310/4885KIF11 3935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.