Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445601 | 0.79 | GAA (0.58) | SMN1; SMN2TSHRHTTGAAKIF11 | |
| SCHEMBL23353436 | 0.79 | HDAC1 (0.51) | KIF11 | |
| SCHEMBL18704720 | 0.78 | KIF11 (0.56) | KIF11 | |
| SCHEMBL23299724 | 0.78 | KIF11 (0.47) | HTTKIF11HPGDLMNA | |
| SCHEMBL12603444 | 0.77 | KIF11 (0.58) | KIF11LMNA | |
| SCHEMBL23299725 | 0.77 | KIF11 (0.46) | MAPTKIF11 | |
| SCHEMBL23299715 | 0.76 | LMNA (0.52) | TSHRKIF11HPGDLMNAKDM4E | |
| SCHEMBL19903787 | 0.76 | HPGD (0.52) | TSHRMAPTHTTKIF11HPGD | |
| SCHEMBL2806972 | 0.75 | L3MBTL1 (0.43) | TSHRKIF11HPGDLMNA | |
| SCHEMBL5571489 | 0.75 | KIF11 (0.41) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475685-B2 | Particle and near-field optical waveguide | KABUSHIKI KAISHA TOSHIBA (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239219-A1 | PARTICLE AND NEAR-FIELD OPTICAL WAVEGUIDE | F2, AHR, CRY1 | SMN1; SMN2 4478/4885TSHR 3330/4885MAPT 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.