Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732106 | 1.00 | CYP2D6 (0.34) | CYP2D6KCNH2HRH3 | |
| SCHEMBL18531920 | 0.95 | CYP2D6 (0.32) | CYP2D6KCNH2HRH3 | |
| SCHEMBL20685148 | 0.93 | CYP2D6 (0.33) | CYP2D6KCNH2HRH3 | |
| SCHEMBL19197834 | 0.91 | EPHX1 (0.33) | CYP2D6KCNH2HRH3 | |
| SCHEMBL2706991 | 0.91 | CYP2D6 (0.38) | CYP2D6KCNH2HRH3 | |
| SCHEMBL20685173 | 0.89 | EPHX1 (0.36) | CYP2D6KCNH2HRH3 | |
| SCHEMBL18460259 | 0.89 | EPHX1 (0.36) | CYP2D6KCNH2HRH3 | |
| SCHEMBL12210956 | 0.83 | CYP2D6 (0.33) | CYP2D6KCNH2HRH3 | |
| SCHEMBL24347883 | 0.82 | CYP2D6 (0.34) | CYP2D6KCNH2HRH3 | |
| SCHEMBL2614325 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180099949-A1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099949-A1 | PYRROLIDINE GPR40 MODULATORS | GPR55, GPR65, GPR4 | CYP2D6 1569/4885KCNH2 2972/4885HRH3 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.