Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10709879 | 0.98 | HSD11B1 (0.31) | HSD11B1HSD11B2IDH1EPHX1 | |
| SCHEMBL21709639 | 0.98 | HSD11B1 (0.35) | HSD11B1HSD11B2CES2CES1EPHX1 | |
| SCHEMBL20824865 | 0.98 | HSD11B1 (0.35) | HSD11B1HSD11B2CES2CES1EPHX1 | |
| SCHEMBL9539732 | 0.91 | IDH1 (0.34) | HSD11B1HSD11B2IDH1 | |
| SCHEMBL21709666 | 0.81 | HSD11B1 (0.33) | HSD11B1HSD11B2CES2CES1 | |
| SCHEMBL298970 | 0.79 | HSD11B1 (0.33) | HSD11B1HSD11B2CES2CES1EPHX1 | |
| SCHEMBL20824845 | 0.77 | MEN1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL7734513 | 0.77 | PEPD (0.42) | — | |
| SCHEMBL20193376 | 0.77 | MEN1 (0.39) | HSD11B1HSD11B2 | |
| SCHEMBL4766405 | 0.77 | PEPD (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065352-A1 | ORGANIC PHOTODETECTOR | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |