SCHEMBL21709666

SCHEMBL21709666

O=C(Cl)C1CC(C2CCCCCCCC2)CCCC(C(=O)Cl)C(C2CCCCCCCCC2)C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.33
HSD11B2 P80365 1/20 0.33
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20043804 0.81 HSD11B1 (0.34) HSD11B1HSD11B2CES2CES1
SCHEMBL10709879 0.79 HSD11B1 (0.31) HSD11B1HSD11B2
SCHEMBL21709639 0.79 HSD11B1 (0.35) HSD11B1HSD11B2CES2CES1
SCHEMBL20824865 0.79 HSD11B1 (0.35) HSD11B1HSD11B2CES2CES1
SCHEMBL21709665 0.77 CES2 (0.46) HSD11B1HSD11B2CES2CES1
SCHEMBL20246940 0.77 CES2 (0.46) HSD11B1HSD11B2CES2CES1
SCHEMBL21949298 0.77 CES2 (0.46) HSD11B1HSD11B2CES2CES1
SCHEMBL20824864 0.77 CES2 (0.46) HSD11B1HSD11B2CES2CES1
SCHEMBL11473350 0.77 ALDH1A1 (0.35) HSD11B1CES2CES1
SCHEMBL5441728 0.73 ALDH1A1 (0.38) HSD11B1HSD11B2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 US disclosed