Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044866 | 0.92 | P2RX7 (0.37) | P2RX7ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20044883 | 0.91 | P2RX7 (0.40) | P2RX7ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL30581574 | 0.91 | TRPM8 (0.41) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18815248 | 0.91 | TRPM8 (0.41) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18281133 | 0.91 | TRPM8 (0.41) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18281125 | 0.91 | TRPM8 (0.46) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18815749 | 0.91 | TRPM8 (0.46) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20044431 | 0.90 | TRPM8 (0.40) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20044043 | 0.89 | TRPM8 (0.39) | TRPM8ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL20044045 | 0.89 | CXCR2 (0.39) | TRPM8P2RX7ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2024-01-25 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2022-04-28 | — | — | US | disclosed |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2020-11-05 | — | — | US | disclosed |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | FMC CORPORATION | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787765-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
| US-20180099935-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
| US-10654804-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
| US-20240025853-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TRPM8 3674/4885P2RX7 869/4885ALDH1A1 1182/4885 |
| US-20220127229-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
| US-20200347017-A1 | SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
| US-11180453-B2 | Substituted cyclic amides and their use as herbicides | NIT2, ARG1, CNPY2 | TRPM8 3664/4885P2RX7 866/4885ALDH1A1 1202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.