SCHEMBL20044975

CCCCCCc1cc(F)c2cc3c(C#C[Si](C(C)C)(C(C)C)C(C)C)c4cc5cc(CCCCCC)cc(F)c5cc4c(C#C[Si](C(C)C)(C(C)C)C(C)C)c3cc2c1

nearest known ligand 0.33

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TLR8	Q9NR97	3/20	0.33

▸	PTGS2	P35354	3/20	0.33

▸	S1PR4	O95977	1/20	0.31

▸	S1PR1	P21453	1/20	0.31

▸	S1PR5	Q9H228	1/20	0.31

▸	CYP3A4	P08684	1/20	0.31

▸	RARB	P10826	2/20	0.30

▸	HTR2A	P28223	1/20	0.30

▸	RARA	P10276	1/20	0.30

▸	RARG	P13631	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20044992	0.85	S1PR4 (0.32)	PTGS2S1PR4S1PR1S1PR5
SCHEMBL20044974	0.82	S1PR1 (0.37)	TLR8PTGS2S1PR4S1PR1S1PR5
SCHEMBL20044991	0.81	KCNH2 (0.32)	—
SCHEMBL21196883	0.79	PTGS2 (0.34)	PTGS2CYP3A4RARBHTR2ARARA
SCHEMBL20044963	0.79	SIGMAR1 (0.37)	TLR8S1PR4S1PR1S1PR5HTR2A
SCHEMBL19462687	0.76	PTGS2 (0.40)	PTGS2S1PR4S1PR1S1PR5CYP3A4
SCHEMBL1884100	0.73	S1PR4 (0.30)	S1PR4S1PR1S1PR5
SCHEMBL20044964	0.73	S1PR1 (0.32)	TLR8S1PR4S1PR1S1PR5
SCHEMBL20044973	0.70	S1PR1 (0.32)	S1PR1
SCHEMBL10058019	0.69	TLR8 (0.35)	TLR8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20180102222-A1	PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME	FUJIFILM CORPORATION (JP)	2018-04-12	—	—	US	disclosed
US-20180102222-A1	PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME	FUJIFILM CORPORATION (JP)	2018-04-12	—	—	US	disclosed