Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20044974 | 0.83 | S1PR1 (0.37) | S1PR4S1PR1S1PR5HSD17B10 | |
| SCHEMBL11959158 | 0.80 | PTGS2 (0.40) | S1PR4S1PR1S1PR5TSHRHSD17B10 | |
| SCHEMBL20044963 | 0.80 | SIGMAR1 (0.37) | S1PR4S1PR1S1PR5 | |
| SCHEMBL20044964 | 0.78 | S1PR1 (0.32) | S1PR4S1PR1S1PR5 | |
| SCHEMBL20044977 | 0.77 | HPGDS (0.34) | TSHRHSD17B10 | |
| SCHEMBL11958257 | 0.75 | NPC1 (0.35) | S1PR1TSHR | |
| SCHEMBL1881062 | 0.74 | RARB (0.38) | S1PR1TSHRHSD17B10 | |
| SCHEMBL2745107 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL20044975 | 0.73 | TLR8 (0.33) | S1PR4S1PR1S1PR5 | |
| SCHEMBL17528653 | 0.72 | HSD17B10 (0.44) | TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935836-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | FALLIS ALEXANDER GRAHAM | 2011-05-03 | — | — | US | disclosed |
| US-7935836-B2 | Compounds comprising a linear series of five fused carbon rings, and preparation thereof | FALLIS ALEXANDER GRAHAM | 2011-05-03 | — | — | US | disclosed |
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | FALLIS ALEXANDER GRAHAM | 2010-01-07 | — | — | US | disclosed |
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | FALLIS ALEXANDER GRAHAM | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004467-A1 | COMPOUNDS COMPRISING A LINEAR SERIES OF FIVE FUSED CARBON RINGS, AND PREPARATION THEREOF | JUP, CDH1, EML4 | S1PR4 3076/4885S1PR1 4262/4885S1PR5 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.