Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21727395 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL13233398 | 0.80 | USP2 (0.32) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL14671182 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL12511593 | 0.77 | ALDH1A1 (0.34) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL11343974 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL11668668 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL6584552 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL13003357 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CHRNB2CHRNB4CHRNA4CA2 | |
| SCHEMBL21756132 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR | |
| SCHEMBL21253928 | 0.73 | TSHR (0.43) | ALDH1A1CHRNB2CHRNB4CHRNA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
| US-20180101106-A1 | CHARGING MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | ULK2, ULK1, ULK3 | ALDH1A1 4012/4885CHRNB2 4377/4885CHRNB4 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.