Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGAV | P06756 | 6/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | BCL2 | P10415 | 3/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2000733 | 0.92 | ITGB3 (0.42) | ITGB3ITGAVITGB5MCL1BRD4 | |
| SCHEMBL12568717 | 0.87 | ITGB3 (0.45) | ITGB3ITGAVITGB5PPARGBRD4 | |
| SCHEMBL12568713 | 0.85 | ITGB3 (0.46) | ITGB3ITGAVITGB5PPARGBRD4 | |
| SCHEMBL12568719 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVITGB5PPARGBRD4 | |
| SCHEMBL4234775 | 0.84 | PPARG (0.55) | ITGB3ITGAVITGB5MCL1PPARG | |
| SCHEMBL1999062 | 0.83 | PPARD (0.40) | ITGB3ITGAVMCL1PPARGBCL2 | |
| SCHEMBL12568445 | 0.82 | ITGB3 (0.45) | ITGB3ITGAVITGB5MCL1PPARG | |
| SCHEMBL12568444 | 0.77 | PPARD (0.37) | ITGB3ITGAVMCL1PPARGBCL2 | |
| SCHEMBL2000563 | 0.75 | ITGB3 (0.44) | ITGB3ITGAVITGB5MCL1PPARG | |
| SCHEMBL2000849 | 0.72 | PPARA (0.42) | ITGB3ITGAVMCL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964622-B2 | Indole acetic acid derivatives and their use as pharmaceutical agents | BAYER HEALTHCARE LLC (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | MA XIN | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298854-A1 | Indole acetic acid derivatives and their use as pharmaceutical agents | IDO1, IDO2, AADAT | ITGB3 4684/4885ITGAV 4461/4885ITGB5 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.