Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364383 | 0.86 | ALDH1A1 (0.39) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL25149388 | 0.86 | ALDH1A1 (0.39) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL11286528 | 0.78 | LMNA (0.46) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL949226 | 0.77 | ALDH1A1 (0.40) | TSHRGAAALDH1A1MAPK1PARP1 | |
| SCHEMBL28316278 | 0.77 | LMNA (0.44) | L3MBTL1LMNATSHRGAAALDH1A1 | |
| SCHEMBL7515941 | 0.69 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1MAPK1PARP1IDO1 | |
| SCHEMBL6002555 | 0.68 | TSHR (0.46) | L3MBTL1LMNATSHRALDH1A1MAPK1 | |
| SCHEMBL6002444 | 0.67 | TSHR (0.47) | L3MBTL1LMNATSHRALDH1A1MAPK1 | |
| SCHEMBL21691192 | 0.66 | PARP1 (0.42) | L3MBTL1GAAALDH1A1MAPK1HPGD | |
| SCHEMBL18659613 | 0.66 | ALDH1A1 (0.44) | GAAALDH1A1MAPK1PARP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018065611-A1 | 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE | Oxford Drug Design Limited (GB) | 2018-04-12 | — | — | WO | disclosed |