Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125639 | 0.89 | ALDH1A1 (0.52) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL13469003 | 0.87 | ALDH1A1 (0.48) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL24709146 | 0.86 | LMNA (0.53) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL13225553 | 0.85 | ALDH1A1 (0.58) | ALDH1A1CNR1HPGDTSHRFAAH | |
| SCHEMBL20022932 | 0.84 | LMNA (0.44) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL13328249 | 0.83 | LMNA (0.60) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL22857301 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAPKMCNR1HPGD | |
| SCHEMBL10036633 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDTSHRFAAH | |
| SCHEMBL12107776 | 0.79 | ALDH1A1 (0.52) | ALDH1A1CNR1HPGDFAAHLPAR1 | |
| SCHEMBL24826063 | 0.79 | CNR1 (0.52) | ALDH1A1LMNAPKMCNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067702-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-12 | — | — | WO | disclosed |