Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP2 | P42575 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20420476 | 0.86 | LMNA (0.51) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL21478093 | 0.86 | ALDH1A1 (0.43) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL20048862 | 0.84 | ALDH1A1 (0.47) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL13328249 | 0.81 | LMNA (0.60) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL20029059 | 0.79 | — | — | |
| SCHEMBL17740055 | 0.79 | ALDH1A1 (0.41) | LMNAPKMALDH1A1HPGDTSHR | |
| SCHEMBL20022935 | 0.78 | CNR1 (0.38) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL24826063 | 0.78 | CNR1 (0.52) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL8942527 | 0.78 | CNR1 (0.54) | LMNAPKMALDH1A1CNR1HPGD | |
| SCHEMBL22015478 | 0.77 | ALDH1A1 (0.41) | LMNAPKMALDH1A1CNR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-11-28 | — | — | US | disclosed |
| US-20200362095-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-19 | — | — | US | disclosed |
| US-10683387-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200362095-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | TRIB1, TRIB2, ABCB11 | LMNA 4117/4885PKM 3677/4885ALDH1A1 1610/4885 |
| US-10683387-B2 | Bottlebrush copolymers and uses thereof | TRIB1, TRIB2, ABCB11 | LMNA 4117/4885PKM 3677/4885ALDH1A1 1610/4885 |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | TRIB1, TRIB2, ABCB11 | LMNA 4117/4885PKM 3677/4885ALDH1A1 1610/4885 |
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | TRIB1, TRIB2, ABCB11 | LMNA 4117/4885PKM 3677/4885ALDH1A1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.