Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27439664 | 0.83 | EIF4A3 (0.33) | EIF4A3 | |
| SCHEMBL21161254 | 0.79 | GRM4 (0.32) | EIF4A3 | |
| SCHEMBL24848632 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL12589415 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL20048894 | 0.68 | NPC1 (0.41) | EIF4A3 | |
| SCHEMBL17807754 | 0.68 | NPC1 (0.38) | — | |
| SCHEMBL12589428 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL12173270 | 0.67 | EIF4A3 (0.42) | EIF4A3 | |
| SCHEMBL18779070 | 0.66 | GCGR (0.33) | — | |
| SCHEMBL24757555 | 0.66 | NOS3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067704-A1 | ISOXAZOLE ANALOGS AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |