Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25584752 | 0.93 | GRIN2B (0.43) | GRIN2BGRIN1CHRNA7 | |
| SCHEMBL20049803 | 0.88 | CHRNA7 (0.47) | GRIN2BGRIN1CHRNA7NPC1 | |
| SCHEMBL20049775 | 0.86 | NPC1 (0.42) | PDGFRBPDGFRAGRIN2BGRIN1CHRNA7 | |
| SCHEMBL20049970 | 0.83 | GRM5 (0.43) | PDGFRBPDGFRAGRIN2BGRIN1NPC1 | |
| SCHEMBL20049908 | 0.83 | CYP1A2 (0.40) | GRIN2BGRIN1CHRNA7NPC1 | |
| SCHEMBL25588074 | 0.82 | CHRNA7 (0.38) | PDGFRBPDGFRACHRNA7NPC1ALDH1A1 | |
| SCHEMBL20049838 | 0.81 | NPC1 (0.38) | GRIN2BGRIN1NPC1ALDH1A1 | |
| SCHEMBL20049978 | 0.81 | CHRNA7 (0.45) | PDGFRBPDGFRAGRIN2BGRIN1CHRNA7 | |
| SCHEMBL20050023 | 0.81 | NPC1 (0.33) | GRIN2BGRIN1CHRNA7NPC1ALDH1A1 | |
| SCHEMBL20050027 | 0.80 | GRIN2B (0.44) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2018067786-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-04-12 | — | — | WO | disclosed |