Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20049943 | 0.80 | MEN1 (0.56) | ABCB1KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL20049942 | 0.74 | ADRB2 (0.51) | KMT2AMEN1OPRM1OPRD1LMNA | |
| SCHEMBL8681927 | 0.67 | MEN1 (0.49) | KMT2AMEN1CYP2D6 | |
| SCHEMBL24433964 | 0.66 | ADRB2 (0.40) | KMT2AMEN1OPRM1OPRD1LMNA | |
| SCHEMBL1803614 | 0.64 | LMNA (0.51) | KMT2AMEN1LMNA | |
| SCHEMBL11606524 | 0.64 | MEN1 (0.71) | KMT2AMEN1OPRM1OPRD1LMNA | |
| SCHEMBL20049936 | 0.63 | POLB (0.57) | KMT2AMEN1LMNACYP2D6 | |
| SCHEMBL18965637 | 0.63 | LMNA (0.44) | KMT2AMEN1LMNAADRB2ADRB1 | |
| SCHEMBL28000803 | 0.63 | LMNA (0.53) | KMT2AMEN1LMNA | |
| SCHEMBL20049939 | 0.63 | MEN1 (0.75) | ABCB1KMT2AMEN1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067685-A1 | SMALL MOLECULE AMPK ACTIVATORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-04-12 | — | — | WO | disclosed |