SCHEMBL18965637

SCHEMBL18965637

C=C/C=C\C=C(/C)OCC(O)COc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
CYP2D6 P10635 3/20 0.43
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
MAPT P10636 3/20 0.40
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HIF1A Q16665 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18887693 0.86 LMNA (0.46) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL22013849 0.78 USP2 (0.48) LMNACYP2D6MEN1KMT2AMAPT
SCHEMBL24494612 0.75 LMNA (0.46) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL19944717 0.75 LMNA (0.43) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL16152341 0.75
SCHEMBL22435464 0.74 LMNA (0.47) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL267463 0.73 LMNA (0.68) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL6351413 0.73 MAPT (0.57) LMNACYP2D6ADRB2ADRB1ADRB3
SCHEMBL24554358 0.73 ELANE (0.34) KMT2AL3MBTL1MAPTTSHR
SCHEMBL25952933 0.73 CYP2D6 (0.43) LMNACYP2D6ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound ADEKA CORPORATION (JP) 2019-01-29 US disclosed
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND ADEKA CORPORATION (JP) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166575-A1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAID COMPOUND RB1, PRMT9, KDM2B LMNA 2393/4885CYP2D6 902/4885ADRB2 3286/4885
US-10189847-B2 Oxime ester compound and photopolymerization initiator containing said compound PPOX, CCNO, MRTO4 LMNA 2693/4885CYP2D6 976/4885ADRB2 3361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.