SCHEMBL2005089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2012201	0.91	CNR1 (0.43)	L3MBTL1LMNAMAPK1KMT2AMEN1
	SCHEMBL3063931	0.90	CNR1 (0.42)	L3MBTL1LMNAMAPK1KMT2AMEN1
	SCHEMBL3065311	0.89	CNR1 (0.40)	L3MBTL1LMNAMAPK1KMT2AMEN1
	SCHEMBL2002863	0.88	L3MBTL1 (0.49)	L3MBTL1NPC1RAB9ATSHR
	SCHEMBL3067596	0.88	L3MBTL1 (0.38)	L3MBTL1LMNAMAPK1KMT2AMEN1
	SCHEMBL3049707	0.86	CETP (0.40)	L3MBTL1KMT2AMEN1POLBHTR6
	SCHEMBL3065182	0.86	CETP (0.38)	L3MBTL1POLBHTR6NPC1RAB9A
	SCHEMBL3053146	0.86	CNR1 (0.44)	L3MBTL1LMNAMAPK1KMT2AMEN1
	SCHEMBL2007289	0.84	MEN1 (0.47)	LMNAMAPK1KMT2AMEN1ALDH1A1
	SCHEMBL2006592	0.84	MEN1 (0.47)	LMNAMAPK1KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.