SCHEMBL2007289

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2006592	1.00	MEN1 (0.47)	MEN1KMT2ALSSHSD11B1HTT
	SCHEMBL4688564	0.92	PKM (0.54)	MEN1KMT2AHSD11B1HTTNPSR1
	SCHEMBL2006326	0.89	ALDH1A1 (0.50)	LSSALDH1A1KDM4EPOLBPKM
	SCHEMBL2010721	0.89	PKM (0.51)	MEN1KMT2AHTTALDH1A1KDM4E
	SCHEMBL2005265	0.89	SMN1; SMN2 (0.48)	MEN1KMT2AHTTALDH1A1KDM4E
	SCHEMBL2009408	0.89	HSD11B1 (0.59)	MEN1KMT2ALSSHSD11B1HTT
	SCHEMBL2008626	0.89	ALDH1A1 (0.60)	MEN1KMT2AHSD11B1HTTALDH1A1
	SCHEMBL2012893	0.88	KMT2A (0.53)	KMT2AHSD11B1HTTALDH1A1POLB
	SCHEMBL2006926	0.88	HSD11B1 (0.58)	MEN1KMT2AHSD11B1ALDH1A1POLB
	SCHEMBL3135656	0.86	GBA1 (0.43)	HSD11B1HTTALDH1A1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.